[HTML][HTML] Corticosterone attenuates reward-seeking behavior and increases anxiety via D2 receptor signaling in ventral tegmental area dopamine neurons

B Peng, Q Xu, J Liu, S Guo, SL Borgland… - Journal of …, 2021 - Soc Neuroscience
… treatment suppresses excitability and synaptic transmission onto VTA dopamine neurons. …
Together, CORT-induced neuronal disruptions in a key region mediating reward-seeking …

Negative allosteric modulation of CB1 cannabinoid receptor signaling suppresses opioid-mediated reward

V Iyer, C Rangel-Barajas, TJ Woodward… - Pharmacological …, 2022 - Elsevier
… The circumscribed allosteric effects of GAT358 may result in endocannabinoid-mediated
self-regulation of dopaminergic neurons that reduces drug reward [80]. Such mechanisms …

Learned avoidance requires VTA KOR-mediated reductions in dopamine

MA Robble, ME Bozsik, DS Wheeler, RA Wheeler - Neuropharmacology, 2020 - Elsevier
dopamine system is known to be essential for rewarddopamine neurons and electrochemical
monitoring of terminal … aversive stimulus and learned suppression of behaviors associated …

Neuroinflammatory response in reward-associated psychostimulants and opioids: a review

S Karimi-Haghighi, S Chavoshinezhad… - Cellular and molecular …, 2023 - Springer
… a crucial role in mediating rewarding behavioral effects of drugs… reward circuit mainly includes
dopaminergic neurons in the … Suppression of the dopamine transporter and, subsequently, …

A brain on cannabinoids: the role of dopamine release in reward seeking and addiction

KZ Peters, EB Oleson, JF Cheer - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
… responses to both reward delivery and reward-predictive … regulation of dopamine signaling
mediating reward-directed … GABA suppression results in disinhibition of the dopamine neuron

A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning

L Shen, GW Zhang, C Tao, MB Seo, NK Zhang… - Nature …, 2022 - nature.com
… a sucrose-induced suppressive response in LHb neurons, which … to LHb 7 mediates the
reward-related suppression in LHb. … such as dopamine neurons is proposed to encode reward

Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice

K Zhou, H Xu, S Lu, S Jiang, G Hou, X Deng… - Nature …, 2022 - nature.com
… of dopaminergic neurons increases dopamine release into … of the PVT-NAc suppresses
reward-seeking and induces … PVT-NAc activation could be mediated by downstream target LH. …

Serotonergic regulation of the dopaminergic system: Implications for reward-related functions

E Courtiol, EC Menezes, CM Teixeira - Neuroscience & Biobehavioral …, 2021 - Elsevier
… From these studies, it appears that activation of this pathway can lead to reinforcement
learning mediated through the excitation of dopaminergic neurons by serotonergic neurons co-…

Heterogeneity in striatal dopamine circuits: Form and function in dynamic reward seeking

AL Collins, BT Saunders - Journal of neuroscience research, 2020 - Wiley Online Library
… , where localized dopamine signals mediate learning about rewarding and threating stimuli
… with low-frequency dopamine neuron stimulation suppresses dopamine release, in line with …

[HTML][HTML] Seeking motivation and reward: Roles of dopamine, hippocampus, and supramammillo-septal pathway

AJ Kesner, CB Calva, S Ikemoto - Progress in neurobiology, 2022 - Elsevier
… Reinforcement learning and goal-seeking behavior are thought to be mediated by
midbrain dopamine neurons. However, little is known about neural substrates of curiosity and …